Original Research Article
Year: 2019 | Month: June | Volume: 9 | Issue: 6 | Pages: 37-46
Study of Fine Needle Aspiration Cytology of Salivary Gland Lesions with Histopathological Correlation
Dr Arjun Namdeo Narote1, Dr. Anjali S. Kulkarni2, Dr Anil R Joshi3
1Resident (Medical Officer), 2Assistant Professor, 3Professor and Head,
Department of Pathology, Government Medical College Aurangabad, Maharashtra, India.
Corresponding Author: Dr. Anjali S. Kulkarni
ABSTRACT
Introduction: Fine Needle Aspiration Cytology (FNAC) is a reliable diagnostic method for evaluation of the lesions salivary glands. The main goal of FNAC of salivary gland lesions is to assist clinicians in the management of patients who present with mass lesions. The present study designed to compare the cytological findings of salivary gland lesions with their histologic diagnoses, in order to assess the sensitivity, specificity, predictive values and diagnostic accuracy of FNAC, with an emphasis on discordant cases in relation with FNAC pitfalls.
Method: present study is prospective study, carried out over 130 case of salivary gland swelling who had undergone FNAC were enrolled. Out of 130patients 77 patients underwent surgery; their histopathological examination was done and correlated with cytological diagnosis.
Results: Most common age group was 21 to 60 years. Mean age for non-neoplastic lesion, benign tumours & malignant tumours was 40.16 years, 45.17 years &53.58 years respectively.
46.15% patients were male and 53.85% patients were female with M: F ratio of 1:1.14.Parotid gland was the most common site of involvement (65.38%) followed by submandibular gland (31.54%). 46.15% lesions were non-neoplastic and 53.85% were neoplastic. Among neoplastic lesions, 65.72% tumours were benign and 34.28% were malignant. The histopathologic correlation was possible in 77 patients. On histopathology pleomorphic adenoma was the most common benign tumours (46.80%) and mucoepidermoid carcinoma was the most common malignant tumour (23.40%). The overall accuracy of cytologic diagnosis in identifying correct lesion was 85.7%. Diagnostic Accuracy for malignant lesions was 68.75%, 100%, 100%, 92.42% &93.50%. Sensitivity and specificity for benign lesions was 96.77% and 95.65 % Sensitivity and specificity for malignant lesion was 68.75% and 100%.
Conclusion - we recommend FNAC study as a preliminary investigation to reliably differentiate neoplastic and non-neoplastic lesions of salivary gland. However, specific histopathologic typing is a must in any doubtful case, more so in malignant lesions.
Key words: wasting, acute malnutrition, under-five children, determinants