Year: 2026 | Month: June | Volume: 16 | Issue: 6 | Pages: 178-185
DOI: https://doi.org/10.52403/ijhsr.20260620
Aerobic Bacteriological Profile of Orthopaedic Device-Related Infections (ODRI) in a Tertiary Care Hospital
Malluri Srivalli1, Swapna Sasapu2, Poosapati Ratna Kumari3
1Post Graduate, Department of Microbiology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India.
2Assistant Professor, Department of Microbiology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India.
3Professor & HOD, Department of Microbiology, Andhra Medical College, Visakhapatnam, Andhra Pradesh, India.
Corresponding Author: Dr. S Swapna
ABSTRACT
Introduction: Orthopedic Device Related Infections (ODRIs) remains a significant complication in modern trauma and orthopaedic surgery leading to implant failure; in severe cases, it may result in amputation and mortality. Clinical outcomes are complicated by the emergence of multidrug resistant bacteria. The present study has been designed to study the microbiological profile and antibiotic sensitivity pattern in patients with orthopaedic device related infections (ODRIs).
Materials And Methods: The present study was a descriptive observational study carried out from November, 2023 - December, 2024 in the department of Microbiology, Andhra Medical College, Visakhapatnam. Samples were collected aseptically from a total of 102 patients with ODRI and were processed according to standard microbiological protocols.
Results: Of the 102 patient samples tested, 60 (59%) were culture positive and 42 (41%) were culture negative. Of the 60 positive cultures, 54 (90%) were monomicrobial, 6 (10%) were polymicrobial isolates. The total bacterial isolates were 66. Among the 66 (100%) bacterial isolates, 17 (26%) were Gram-positive cocci and 49 (74%) were Gram-negative bacilli. The most common bacteria isolated were Staphylococcus aureus 16 (24%) followed by Pseudomonas aeruginosa 14 (21%). Among the 49 Gram negative bacilli, 26 (53%) were ESBL producers. Among 16 S. aureus isolates, 10 (63%) showed methicillin resistance.
Conclusion: This study emphasizes the importance of aggressive early management of ODRIs, strict adherence to aseptic surgical techniques, routine screening for drug resistant organisms, and the need for tailored antimicrobial strategies.
Key words: Implant, Staphylococcus aureus, Pseudomonas aeruginosa, MRSA, ESBL