Year: 2026 | Month: May | Volume: 16 | Issue: 5 | Pages: 131-140
DOI: https://doi.org/10.52403/ijhsr.20260516
Evaluation of Bladder Wash Cytology and Its Correlation with Histopathology in Diagnosing Neoplastic Lesions of the Urinary Bladder
Rama Das1, Pallabi Purakayastha2, Partha Pratim Deb3
1Associate Professor, Department of Pathology, North Bengal Medical College & Hospital, Siliguri, West Bengal, India
2Junior Resident, Department of Pathology, North Bengal Medical College & Hospital, Siliguri, West Bengal, India
3Assistant Professor, Department of Urology, North Bengal Medical College & Hospital, Siliguri, West Bengal, India
Corresponding Author: Pallabi Purakayastha
ABSTRACT
Background: Urinary cytology is a proven non-invasive diagnostic modality used in The Paris System (TPS) for detecting urothelial carcinoma especially high-grade lesions. Bladder wash cytology (BWC) offers better cellularity than voided urine samples, and could improve the diagnostic accuracy.
Objectives: To assess the diagnostic value of the BWC using TPS, to compare the cytological results with the histopathological results in suspected patients of urinary bladder neoplasms.
Methods: This study was an observational study that was carried out in a tertiary care hospital from 2023 to 2025 with 82 participants having urinary bladder lesion. Before transurethral resection or biopsy, bladder washings were collected and processed by conventional cytospin methods. The cytology interpretations were compared with Histopathological diagnosis. The statistical analysis was done using SPSS version 30.
Results: Seventy-eight cases were available in the form of histopathological correlation. The most frequent cytology diagnosis was high-grade urothelial carcinoma. BWC showed sensitivity of 98.2, specificity of 90.9, diagnostic accuracy of 96.1% and p value <0.0001.
Conclusion: BWC has highly diagnostic value for diagnosing high-grade urothelial carcinoma, and being a useful complement to histopathology in the assessment and follow-up cases of bladder neoplasm.
Key words: Bladder wash cytology, The Paris System, Cytospin method, Urothelial carcinoma of bladder.