Year: 2026 | Month: May | Volume: 16 | Issue: 5 | Pages: 19-29
DOI: https://doi.org/10.52403/ijhsr.20260503
An Analysis of Serum Triglyceride and Electrolytes Levels among Posterior Subcapsular Cataract Patients Attending a Tertiary Care Teaching Hospital of Tripura, North East India - An Observational Study
Maitri Roy1, Dipanwita Roy2, Partha Sarathi Pal3, Phani Sarkar4
13rd year PGT, Department of Biochemistry, Agartala Government Medical College and Govind Ballabh Pant Hospital, Agartala, Tripura, India,
2Senior Resident, Department of Biochemistry Agartala Government Medical College and Govind Ballabh Pant Hospital, Agartala, Tripura, India,
3Associate Professor, Department of Biochemistry, Agartala Government Medical College and Govind Ballabh Pant Hospital, Agartala, Tripura, India,
4Prof. & HOD, Department of Ophthalmology, Agartala Government Medical College and Govind Ballabh Pant Hospital, Agartala, Tripura, India,
Corresponding Author: Dr. Maitri Roy
ABSTRACT
Background: Posterior subcapsular cataract (PSC) represents a visually disabling subtype of age-related cataract that is frequently associated with metabolic and biochemical disturbances. Although dyslipidaemia and electrolyte imbalance are implicated in cataractogenesis, there is a lack of regional data from Northeast India.
Aim: To evaluate the clinico-biochemical profile of PSC patients with emphasis on serum triglyceride and electrolyte levels.
Methods: A cross-sectional observational study was conducted among 140 PSC patients aged 50–80 years attending AGMC & GBP Hospital, Tripura. Serum triglycerides, sodium, potassium, and chloride were estimated using standardised enzymatic and ion-selective electrode methods. The chi-square test was used to assess the significance of the association between two or more risk factors, while the student’s t-test was applied to evaluate the significance of the difference between two means. A p-value of less than 0.05 was considered statistically significant.
Results: Elevated serum triglycerides & chloride levels are observed in 81.4% (OR = 6.58, p < 0.001) and 77.9% (OR = 5.27, p < 0.001) of study participants, respectively. Sodium imbalance is also noted in 40% (OR = 2.14, p = 0.001) of cases. Age and gender significantly influence triglyceride and chloride levels, with higher levels in older females.
Conclusion: Hypertriglyceridemia and hyperchloremia are strongly associated with PSC, while sodium imbalance also contributes significantly. These findings highlight the importance of integrating biochemical screening into cataract prevention and management strategies in Northeast India.
Key words: Posterior subcapsular cataract, triglycerides, chloride, sodium, dyslipidaemia, electrolyte imbalance, Tripura