Year: 2026 | Month: April | Volume: 16 | Issue: 4 | Pages: 281-287
DOI: https://doi.org/10.52403/ijhsr.20260435
Clinical Correlation of Cardiac Dysfunction with Severity of Liver Disease in Liver Cirrhosis Patients: A Hospital-Based Cross-Sectional Observational Study
Gurmeet Singh Yadav1, Amresh Kumar Agarwal2
1,2Department of General Medicine,
Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, India.
Corresponding Author: Dr. Gurmeet Singh Yadav
ABSTRACT
This study aimed to investigate clinical correlation of cardiac dysfunction in liver cirrhosis patients with Child Pugh score.
Objectives: 1) To analyze and document the cardiac abnormalities in cirrhotic patients. 2) To correlate these cardiac findings with severity of liver disease.
Methodology: This hospital-based cross sectional observational study was conducted on adult patients with cirrhosis at SRMS Institute of Medical Sciences, Bareilly, UP. Data on demographic information, medical history, clinical characteristics, and laboratory tests were collected using a structured questionnaire, Liver cirrhosis was diagnosed as per biochemical, ultrasonographic, and clinical criteria. 2D echocardiography and 12-lead ECG were used for cardiac evaluation. All subjects underwent Child-Pugh scoring.
Results: The mean age of the patients was 57.11 ± 12.40 yrs. Most patients were male (91%). The predominant etiological cause of liver cirrhosis was alcoholic liver disease (74%). Ascites was present in 78%patients. Hepatic encephalopathy was observed in 11% patients. Jaundice was present in 61%, while pedal edema and fatigue/dyspnea were noted in 46% and 51% cases respectively. Most patients belonged to B Child–Pugh Class (47.8%). QTc prolongation prevalence increased progressively with disease severity.
Conclusion: Most liver cirrhosis patients were male, with leading etiological factor as the alcoholic liver disease and cardiac involvement being commonly manifesting as DDF and electrical conduction abnormalities. More than half of the cohort had DDF. The severity of diastolic indices was progressively increased across CPC. The severities of liver disease (CPC) and DDF were strongly correlated.
Key words: Cardiac dysfunction, Liver cirrhosis; Child Pugh score; Alcoholic liver disease; Ascites; Hepatic encephalopathy