Year: 2026 | Month: April | Volume: 16 | Issue: 4 | Pages: 106-111
DOI: https://doi.org/10.52403/ijhsr.20260414
Effect of Interaction Between Lignocaine-Adrenaline and Sodium Hypochlorite on Coronal Seal of Post-Endodontic Restorations - An in vitro Study
Pooja Jain1, Kundana Racha2, Sarjeev Singh Yadav3, Kavitha Anantula4, Bhavana Vankayala5, Manisha Chouhan6
1,2,3,4,5,6Department of Conservative Dentistry & Endodontics,
Government Dental College & Hospital, Hyderabad, India.
Corresponding Author: Pooja Jain
ABSTRACT
Intrapulpal injection is a commonly used supplemental anaesthetic technique in endodontics, and sodium hypochlorite (NaOCl) remains the gold-standard irrigant. The interaction between lignocaine–adrenaline and NaOCl produces a white precipitate that may reduce available chlorine and occlude dentinal tubules, potentially compromising the coronal seal of restorations. This in-vitro study evaluated the effect of this interaction on the coronal seal of endodontically treated teeth. Forty-five extracted single-rooted premolars were divided into three groups based on irrigant protocol: saline, 3 % NaOCl, and saline followed by 3 % NaOCl. After cleaning and shaping, obturation and composite restoration, specimens were immersed in 2 % methylene blue for seven days and dye penetration assessed under a stereomicroscope. Teeth irrigated with NaOCl exhibited significantly greater dye penetration compared with the other groups, indicating a compromised coronal seal.
Key words: Coronal leakage; Intrapulpal injection; lignocaine hydrochloride; sodium hypochlorite.