Year: 2026 | Month: April | Volume: 16 | Issue: 4 | Pages: 90-95
DOI: https://doi.org/10.52403/ijhsr.20260412
Peripheral Neuropathy in Hyperthyroidism - A Case Control Study
Sudha S1, Parvatha Rani N2, Balasubramaniam K3
1Associate Professor, Institute of Physiology, Madurai Medical College
2Professor, Department of Physiology, KMMC Medical College, Muttom
3Assistant Professor, Department of Physiology, ESI MC& Hospital, Bihta, Bihar, India
Corresponding Author: Dr. S. Sudha
ABSTRACT
Background: Thyroid hormone is the one that exhibits its effect on all the cells in our body. So any dysfunction of thyroid gland secretion either decreased or increased has its effects on all the systems in our body. There are many studies in hypothyroidism and nervous system and only few studies done in patients with hyperthyroidism as neuropathy is found to be uncommon in hyperthyroidism.
Aim: To perform Nerve Conduction Study in Hyperthyroid female subjects and age matched controls and compare the results.
Materials and Methods: This is a case control study conducted in Tirunelveli Medical College Hospital after getting IEC approval. The study was performed in 18 newly diagnosed hyperthyroid female patients and 25 control subjects. The mean age of Hyperthyroid patients is 34.72 + 8.75 and control is 36.52 + 8.10. The sensory nerve conduction study was performed in Sural, Median and Ulnar nerve. The motor nerve conduction study was performed in Posterior Tibial, Median and Ulnar nerve. The nerve conduction studies were done using RMS EMG EP MARK II at Neurophysiology lab.
Results: The nerve conduction study parameters like Latency, Conduction Velocity and Amplitude of motor and sensory nerve of Hyperthyroid and control subjects were compared and statistical analysis done by unpaired t test. There was a statistically significant difference between hyperthyroid and control subjects predominantly in sensory nerve conduction study. Sensory neuropathy was present in 61% and sensorimotor neuropathy in 5.5% and carpal tunnel syndrome in 17% of hyperthyroid subjects.
Conclusion: It is essential to include nerve conduction study as a routine in hyperthyroid patients also.
Key words: Hyperthyroidism, Nerve conduction study, Amplitude, Latency, Conduction velocity