Year: 2026 | Month: April | Volume: 16 | Issue: 4 | Pages: 70-77
DOI: https://doi.org/10.52403/ijhsr.20260409
A Study of Clinical and Renal Profile in Poisonous Snake Bite Victims Attending a Tertiary Care Hospital in Assam
Arju Saikia1, Roshmi Rekha Gogoi2
1Assistant Professor, Department of Biochemistry, Pragjyotishpur Medical College and Hospital, Guwahati, Assam, India
2Assistant Professor, Department of Emergency Medicine, Nagaon Medical College and Hospital, Nagaon, Assam, India
Corresponding Author: Arju Saikia
ABSTRACT
Background: Snakebite is a significant occupational and environmental hazard in Assam, with one of the highest reported incidences of snakebite in the country. Despite this burden, data on comprehensive clinical and renal profiles from this region remain limited.
Objectives: To evaluate clinical and renal parameters in poisonous snakebite patients and compare them with controls at a tertiary care hospital in Assam.
Methods: A hospital-based comparative observational study was conducted at Nagaon Medical College and Hospital (NMCH), Nagaon, Assam, over six months following ethics committee approval. Forty clinically confirmed poisonous snakebite patients (cases) were enrolled alongside forty age- and sex-matched healthy controls. Clinical examination was done and serum glucose, urea and creatinine were measured. Statistical analysis was performed using Student's t-test; p <0.05 was considered significant.
Results: The mean age of cases was 35.45±13.56 years and males predominated (57.5 %). Haemotoxic envenomation was the most common type (56.7%). Serum urea (52.87± 30.25 vs 38.16 ± 13.36 mg/dL) and creatinine (1.93 ± 1.58 vs 0.85 ± 0.25 mg/dL) were significantly elevated in cases (p<0.05). Vomiting was seen in 55% of the cases. Elevated renal parameters were seen in 27.5% of cases.
Conclusion: Poisonous snakebite in Assam causes significant derangements in renal parameters with high chances of progression to renal failure. Renal involvement is a major morbidity determinant, especially in haemotoxic envenomation. Early biochemical screening and prompt management are essential to reduce snakebite-related mortality in this high-burden region.
Key words: Snakebite, Envenomation, Renal profile, Acute kidney injury