Year: 2026 | Month: April | Volume: 16 | Issue: 4 | Pages: 8-16
DOI: https://doi.org/10.52403/ijhsr.20260402
Serum Lipoprotein (a) Levels in Patients with Ischemic Stroke
Priya Theresa Job1, T. Sobhakumari2, Thomas Iype3
1,2Department of Physiology, 3Department of Neurology,
Govt. Medical College, Thiruvananthapuram, KUHS University, Kottayam, India.
Corresponding Author: Dr. Priya Theresa Job
ABSTRACT
Introduction: A great number of studies have suggested that high levels of Lipoprotein (a) Lp (a) [Lp (a)] predispose the individuals to atherosclerotic vascular diseases specifically, ischemic stroke and coronary artery disease. But only a few studies have investigated the distribution of serum Lp (a) levels in the Indian population so far. In the present study, an attempt has been made to find out the levels of serum Lp (a) in a group of newly diagnosed ischemic stroke patients.
Objective: To study the serum levels of Lipoprotein (a) in patients who developed ischemic stroke in comparison with a group of people who do not have the clinical outcome.
Methods: The levels of serum Lp (a) were measured in forty newly diagnosed ischemic stroke patients, aged 45-60 yrs, who were admitted to the Department of Neurology, Government Medical College Thiruvananthapuram.
Results: The mean ± SD of Lp (a) in stroke patients was 24.76 ±10.74 whereas in person without stroke it was 17.44 ±10.50. This difference was statistically significant. (p<0.05) Among the stroke patients 37.5% had Lp (a) values >30mg/dl and among persons without stroke only 12.5% had elevated Lp (a) values. The difference was statistically significant. (p<0.05). The current research has observed no significant correlation of serum Lipoprotein (a) and other markers like blood pressure, fasting blood glucose, total cholesterol, LDL –c, HDL –c, triglycerides and BMI.
Conclusion: The study revealed that the mean serum Lp (a) levels in patients with stroke were significantly higher than persons without stroke.
Key words: Lipoprotein (a), stroke, ischemic stroke