Year: 2025 | Month: December | Volume: 15 | Issue: 12 | Pages: 154-158
DOI: https://doi.org/10.52403/ijhsr.20251220
Bacterial Uropathogens and Their Antibiogram Among In-Patients in a Tertiary Health Care Center, Siddipet, Telangana
Pavani Kalagara1, R Saraswati Jayanthi2, Qursheed Sultana3
1Professor & HOD, Department of Microbiology, RVMIMS & RC, Siddipet, Telangana
2Professor, Department of Microbiology, RVMIMS & RC, Siddipet, Telangana
3Professor, Department of Microbiology, RVMIMS & RC, Siddipet, Telangana
Corresponding Author: Dr. Pavani Kalagara
ABSTRACT
Background: Urinary tract infections (UTIs) are the most common healthcare-associated infections. Objective of the study is to determine the bacteriological profile and antibiotic susceptibility pattern of uropathogens to frame better antibiotic policy, which is essential for practicing antimicrobial stewardship.
Materials and Methods: This was a retrospective descriptive study done at the Department of Microbiology, RVMIMS &RC, Siddipet, Telangana in which analysis of the bacterial culture isolates obtained from urine samples received between January 2024 to December 2024 of in-patients was performed.
Results: Out of 1401 urine samples from inpatients with signs and symptoms of urinary tract infection, 266 (18.9%) showed significant growth on culture. Female preponderance was noticed. Most common causative organism found in our study was Escherichia coli (53.75%) followed by Enterococcus species (21.4%) and Klebsiella pneumoniae (11.6 %). Escherichia coli isolates showed susceptibility of 94% to fosfomycin; 77% to Nitrofurantoin, and 64% to Carbapenems. The susceptibility percentage of Klebsiella pneumonia isolates, for nitrofurantoin and carbapenems was 38% and 44% respectively. Enterococcus species isolates were 33% susceptible to Fosfomycin and 75% susceptible for Nitrofurantoin. MDR
Conclusion: Escherichia coli followed by Enterococcus species are the most common uropathogens. Nitrofurantoin is the most effective antibiotic against uropathogens like Escherichia coli, Enterococcus species and Staphylococcus aureus. Klebsiella pneumoniae and Acinetobacter baumanni exhibited higher rate of multi-drug resistance.
Key words: Urinary tract infection (UTI), multidrug resistant organisms (MDRO), antibiotic susceptibility testing (AST)