Year: 2025 | Month: November | Volume: 15 | Issue: 11 | Pages: 148-156
DOI: https://doi.org/10.52403/ijhsr.20251119
Decoding the Phytochemical Treasure and Physicochemical Properties of Distimake quinquefolius L. for Herbal Drug Development
Srikeerthivasan. C1, Dr. V. R. Ravikkumar2, Mahalakshmi. S3, Loganayagi. M4, Maheswari. V5
1,3PG Student, Department of Pharmacognosy, The Erode College of Pharmacy, Erode-638112, Affiliated to The Tamil Nadu Dr.M.G.R. Medical University, Chennai-600032, Tamil Nadu, India.
2Professor & Head, Department of Pharmacognosy, The Erode College of Pharmacy, Erode-638112, Affiliated to The Tamil Nadu Dr.M.G.R. Medical University, Chennai-600032, Tamil Nadu, India.
4,5Assistant Professor, Department of Pharmacognosy, The Erode College of Pharmacy, Erode-638112, Affiliated to The Tamil Nadu Dr.M.G.R. Medical University, Chennai-600032, Tamil Nadu, India.
Corresponding Author: Srikeerthivasan. C
ABSTRACT
Distimake quinquefolius L. (Convolvulaceae) is a perennial climbing herbaceous vine reaching up to 5 m, characterized by palmately compound leaves with five elliptic to lanceolate leaflets and trumpet-shaped white flowers with faint off-white stripes. The species grows predominantly in disturbed habitats such as roadsides and agricultural fields. Physicochemical evaluation revealed total ash (8% w/w), acid-insoluble ash (0.5% w/w), water-soluble ash (4.5% w/w), and sulphated ash (9% w/w). Extractive values were found to be 19.2% w/w (water-soluble) and 9.6% w/w (alcohol-soluble), loss on drying (9.2% w/w), foaming index (<100), swelling index (3.5 cm), and heavy metal content. Phytochemical investigations confirmed the presence of alkaloids, phenols, tannins, flavonoids, triterpenoids, and steroids. GC–MS analysis revealed that presence of potential bioactive compounds of pharmacological relevance. Collectively, these findings indicate that Distimake quinquefolius L. possesses significant phytoconstituents and favorable physicochemical attributes, justifying further pharmacological and therapeutic studies.
Key words: Distimake quinquefolius L., Physicochemical, Phytochemical, GC-MS Analysis.