IJHSR

International Journal of Health Sciences and Research

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Year: 2023 | Month: October | Volume: 13 | Issue: 10 | Pages: 353-357

DOI: https://doi.org/10.52403/ijhsr.20231046

CytoSorb® in Combination with CRRT in A Patient Suffering from Septic Shock, Acute Respiratory Distress Syndrome (ARDS) and Acute Kidney Injury (AKI): A Case Report

Dr Gauri Shankar Sharma1, Dr Madhvi Narwal2

1MD, FRCP, FNB, Critical Care Medicine, Director & Head, Fortis Hospital Vasant Kunj, New Delhi, 110070
2MBBS DA Idccm, Critical Care Medicine, Associate Consultant Venkateshwar Hospital, Dwarka, New Delhi, 110075

Corresponding Author: Dr Gauri Shankar Sharma

ABSTRACT

OBJECTIVE: We report a case of a patient suffering from septic shock with acute kidney injury (AKI) and acute respiratory distress syndrome (ARDS) treated with standard medical treatment and CRRT, as well as adjuvant extracorporeal hemoadsorption device called CytoSorb® to address the cytokine storm.
CASE PRESENTATION: This case outlines a 53-year-old female patient who was admitted to the hospital with fever and chills, loose stool, vomiting and severe weakness. On admission, she was feverish, hypotensive, with tachycardia, tachypnea, and hypoxic. Vasopressor were started to keep mean arterial pressure (MAP) stable. Chest scan revealed infiltrates, with pleural effusion. she was intubated and placed on mechanical ventilation due to work of breathing (WOB). Later, urine output dropped to anuric levels, followed by acidosis, necessitating the start of Continuous renal replacement therapy (CRRT). Adjuvant CytoSorb® was started due to the condition's deterioration and resistance to therapy.
RESULTS: Post two sessions of CytoSorb®, there was rapid improvement in hemodynamic stability, improvement in respiratory functions, reduction in vasopressors, and decrease in blood lactate.
CONCLUSION: Adjuvant CytoSorb® therapy in conjunction with standard treatment and CRRT was found to be a safe and effective therapeutic alternative in a patient suffering from septic shock, ARDS, and AKI.

Key words: Acute kidney injury, Acute respiratory distress syndrome, CytoSorb, Cytokines, Hemoadsorption, Sepsis, Septic shock

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