Original Research Article
Year: 2019 | Month: September | Volume: 9 | Issue: 9 | Pages: 325-329
Association of Hypothyroidism in Pregnant Women with Hyperglycaemia
Heena Parveen1, Anisa M. Durrani2, S. Manazir Ali3, Nasreen Noor4
1Research Scholar, Department of Home science, Aligarh Muslim University, Aligarh, India.
2Professor, Department of Home science, Aligarh Muslim University, Aligarh, India.
3Professor, Department of Paediatrics, J.N. Medical College, AMU, Aligarh, India.
4Assistant Professor, Department of Obstetrics and Gynaecology J.N, Medical College, AMU, Aligarh, India.
Corresponding Author: Heena Parveen
ABSTRACT
Background: Globally, prevalence of hyperglycaemia in pregnancy ranges varies widely, from 1% to 28%, hypothyroidism ranges from 4.8-11% in India during pregnancy. An effort is being made to look at both these complications in unification rather than in segregation.
Purpose: Purpose of the study was to determine the association between hypothyroidism and hyperglycemia, as well as the prevalence of hypothyroidism in pregnant women with hyperglycemia. Materials and methods: Semistrutured interview were conducted with pregnant women (n= 250) attending antenatal OPD at Jawaharlal Nehru Medical College and hospital, Aligarh. The descriptive statistics and Pearson correlation method was performed and data were analysed with IBM SPSS software.
Results: The following results were derived: (1) Prevalence of GDM and hypothyroidism during pregnancy; (2) Association between hypothyroidism and GDM among pregnant women. 57 of the 250 subjects enrolled to take part in the study (22.8%) were diagnosed with GDM, while 193 (77.2%) revealed a normal glucose tolerance. TSH levels were available for all 250 subjects in this study, 38 (15.2%) of whom were diagnosed with hypothyroidism. 19 (19/57 or 33.3%) subjects who were diagnosed with GDM, were also hypothyroid. That showed a significant association existed between TSH levels greater than 2.5 µIU/L and blood plasma glucose levels greater than 140 mg/dL (p value = 0.01).
Conclusion: There is a considerably squat prevalence (33.3%) of hypothyroidism in pregnant women who have been diagnosed with GDM. This study expands to the growing literature regarding the dual endocrinopathy in pregnant women and makes a case for increased observation of pregnant women diagnosed with either endocrinopathy.
Key words: Gestational Diabetes Mellitus, Hypothyroidism, WHO, Association.