Original Research Article
Year: 2019 | Month: September | Volume: 9 | Issue: 9 | Pages: 9-14
Effect of Coenzyme Q10, Riboflavin, Niacin, Selenium (CoRNS) and Emblica officinalis on Lysosomal Enzymes Studied on Experimental Atherosclerosis
U. Indumathi1, Dr. T. P. Sachdanandam2
1Department of Biochemistry, J.N.N Arts and Science Women’s College, University of Madras.
2Department of Pathology, Dr. ALM. PGIBMS, Taramani, Chennai-600113.
Corresponding Author: U. Indumathi
ABSTRACT
Objective: Our study was aimed to show the effect of nutraceuticals such as Coenzyme Q10, Riboflavin, Niacin and Selenium (CoRNS) and Emblica officinalis on high cholesterol diet (HCD) induced atherosclerotic rat model and to show the effect of this formulated drug on the activity of lysosomal enzymes and protein bound carbohydrate (PBC).
Method: The atherosclerotic induced rats were treated with (CoRNS) and Emblica officinalis and the activities of the lysosomal enzymes and protein bound carbohydrates were studied.
Result: Treatment with (CoRNS) and Emblica officinalis has decreased the activity of the lysosomal enzymes and PBC.
Conclusion: The atherosclerotic rats were brought to normal conditions on treatment with (CoRNS) and Emblica officinalis.
Key words: cardiovascular disease, cathepsin, hexosamine and hexuronic acid, hexose.