IJHSR

International Journal of Health Sciences and Research

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Case Report

Year: 2017 | Month: January | Volume: 7 | Issue: 1 | Pages: 307-309

Cholestatic Jaundice Induced by Sequential Carbimazole and Propylthiouracil Treatment for Thyrotoxicosis-A Case Report

N.S.NEKI1, Satpal Aloona2

1Prof Medicine 2Assistant Prof Medicine,
Govt. Medical College/Guru Nanak Dev Hospital, Amritsar, 143001, Punjab, India.

Corresponding Author: N.S.NEKI

ABSTRACT

Grave’s disease is the most common cause of hyperthyroidism. Antithyroid drugs are usually well tolerated in majority of patients but dangerous adverse effects can occur in 3-12% of treated patients. Cholestatic jaundice is a rare but potentially fatal complication secondary to the use of antithyroid drugs like carbimazole and propylthiouracil. We report a case of 46 year old male patient who developed cholestatic jaundice following sequential administration of carbimazole and propylthiouracil treatment for thyrotoxicosis.

Key words:Thyrotoxicosis; Cholestatic jaundice; Carbimazole; Propylthiouracil.

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