Original Research Article
Year: 2016 | Month: November | Volume: 6 | Issue: 11 | Pages: 93-99
Ocular Pathogen Causing Bacterial Keratitis in a Tertiary Care Rural Hospital
Ranjana Ramdas Khorgade1, Anil A. Gaikwad2, S.L. Nilekar3
1Assistant Prof., Dr. P.D.M.M.C, Amravati, 2Asso. Prof., GMC, Aurangabad, 3Prof. & Head, S.R.T.R GMC, Ambajogai.
Corresponding Author: Ranjana Ramdas Khorgade
ABSTRACT
Introduction: Corneal blindness is a major public health problem in India. Morbidity can be significantly reduced when the treatment modality is guided by the knowledge of the causative organism & its antimicrobial susceptibility.
Aims & Objectives:
- To isolate the bacteria causing keratitis & study the antibiotic sensitivity pattern of isolates.
- To study predisposing factors causing keratitis.
Materials & Methods: A prospective study was employed from December 2010 to December 2012 from which a total of 97 patients with keratitis were included in the study. Corneal scrapings collected were transported and microbiologically processed using standard operating procedure.
Result: Out of 97 cases, keratitis showed the highest 30 (31%) cases were in the age group of 41-50 years with male preponderance. Out of 44 positive cultures 21 (21.64%) were bacteria, 21(21.64%) were fungi & 2(2.06%) were mixed. The most important predisposing factor in the present study was trauma in 86 cases (88.65%). Among the isolates 6 (26.08%) were Staphylococcus aureus, 3 (13.04%) were CONS, 6 (26.08%) were Pseudomonas, 4 (17.39%) were Klebsiella, 2 (8.69%) were each of Proteus mirabilis & Proteus vulgaris. Gram positive cocci were sensitive to Erythromycin, Gentamicin with resistance to Ciprofloxacin & Cefoxitin. Gram negative isolates were sensitive to Ciprofloxacin, Gentamicin & resistant to Amoxclave.
Conclusion: Routine microbiological examination of corneal ulcer is necessary to analyze & compare the changing trends in the microbial etiology & their susceptibility pattern to formulate a proper & appropriate antibiotic response against corneal ulcer.
Key words: keratitis, CONS, antibiotics.