Year: 2024 | Month: January | Volume: 14 | Issue: 1 | Pages: 93-101
DOI: https://doi.org/10.52403/ijhsr.20240112
Treatment and Strategy for Food Allergies in Paediatrics
Dr. Sana Shaikh1, Dr. Ab Samad2, Ab Haque Bamer3, Sunil S. Tade4, Areeb Inamdar5, Dr. Bijoy Panda Kumar6, Dr. Shuklendu Deo7
1Medical Information Specialist, Department of Medical Communications, Eversana (India) PVT. Ltd, Pune,
2Medical Advisor Department of Medical Affairs, Celagenex Research (India) PVT. Ltd, Thane,
3Associate Professor Department of Pharmacology, Vivekvardhini Sevabhavi Sansthas College of Pharmacy at Post Pingali, Parbhani,
4Associate Professor Department of Pharmaceutics Vivekvardhini Sevabhavi Sansthas College of Pharmacy at Post Pingali, Parbhani,
5Department. of Biology-Biotechnology, Maulana Azad College of Arts, Science and Commerce, Dr. Rafiq Zakaria Campus, Aurangabad,
6Department of Pharmacy Practice, Krishna Institute of Pharmacy, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad,
7MS Regulatory Affairs College of Professional Studies Northeastern University Boston Ma 02115,
Corresponding Author: Dr. Sana Shaikh
ABSTRACT
Food allergy (FA) has significantly increased in the last decade, and its diagnosis is a continuous challenge. Mild cases are often neglected or detected late, and in children, parents may not be able to accurately interpret symptoms. It is crucial to differentiate FAs from food intolerance and toxic reactions. To provide personalized management, accurate diagnosis is essential. Modern diagnostic tests, such as component diagnosis and epitope reactivity, allow for a more accurate therapeutic approach and reliable prognosis evaluation. Investigations like serum IgE, elimination diets, oral food challenges, single, blind, and double-blind tests, and skin tests are used. Anaphylaxis risk can be assessed using molecular diagnostics/component-resolved diagnosis (CRD) and a basophilic activation test (BAT). These tests allow for planned, individualized therapy based on molecular and clinical characteristics. Understanding immunological processes, diagnostics, and immunotherapies in FAs is crucial for evaluating food allergen exposure, detecting allergic responses, analyzing clinical manifestations, highlighting diagnostic options, and demonstrating appropriate therapeutic strategies.
Key words: Food allergy, paediatric, basophilic activation test, component-resolved diagnosis