Case Report
Year: 2023 | Month: February | Volume: 13 | Issue: 2 | Pages: 85-89
DOI: https://doi.org/10.52403/ijhsr.20230214
Aggressive Central Giant Cell Granuloma of the Mandible - A Case Report with Diagnostic Dilemma
Ajay Sutare1, Ajay Pratap Singh Parihar2, Prashanthi Reddy3, Varsha A.C.4
1,4PG student, 2Professor and Head, 3Reader;
Department of Oral Medicine and Radiology, Government College of Dentistry Indore, Madhya Pradesh, INDIA
Corresponding Author: Ajay Sutare
ABSTRACT
Central giant cell granuloma (CGCG) is an uncommon, intraosseous, osteolytic, bony lesion of the jaw which is predominantly seen under the age of 30 years with female predominance and is common in the mandibular anterior region. The clinical behavior of the CGCG ranges from slow-growing asymptomatic to large-growing symptomatic osteolytic lesions. The etiology of CGCG is debatable, although, local trauma, inflammation, and hemorrhage have been suggested. Here is a presentation of a case report showing aggressiveness of CGCG with rapid growth involving the anterior region of the mandible associated with paresthesia, pain, mobility, cortical perforation, and showing a completely osteolytic nature. It was diagnosed by histopathological examination and immunohistochemistry. This case was treated surgically with no recurrence seen after a one-year follow-up with a good prognosis. Expansile and osteolytic bony lesions in the jaws or any radiolucency more than 2 cm CGCG should take into consideration as a differential diagnosis.
Key words: Aggressive and non-aggressive lesions, Central giant cell granuloma, Diagnostic dilemma, follow-up, Recurrence