Original Research Article
Year: 2023 | Month: January | Volume: 13 | Issue: 1 | Pages: 187-190
DOI: https://doi.org/10.52403/ijhsr.20230126
Comparison the Level of the IL-20 Cytokine in Gingival Crevicular Fluid in Periodontally Health and Periodontitis Patients
Dr.Maha Asaad Amin Munshi1, Dr.Mohammed Abdullah Batwa2, Dr.Abdullah Ahmed Ali Agilley3, Dr.Reem Ali Ayedh Alshamrani4
1Senior Register-Periodontics Ministry of Health- Jeddah-K.S. A
2Consultant-Periodontics Ministry of Health-Jeddah-K.S. A
3Resident- Saudi periodontics Board Ministry of Health-K.S. A
4General Dentist-Jeddah – K.S.A
Corresponding Author: Dr.Mohammed Abdullah Batwa
ABSTRACT
Background: Periodontitis refer to the inflammation of the tissues surrounding tooth structure. Multiple cytokines are involved in the pathogenesis of periodontitis.
Objectives: A comparison of the IL-20 level found in gingival crevicular fluid in healthy and periodontitis patients.
Methods: GCF samples were obtained from both patients systematic healthy with periodontitis and with healthy periodontium patients. The subjects included in this study were divided into two equal groups: group 1: included 10 patients with stage 3-4 periodontitis and group 2: included 10 periodontally healthy subjects. The GCF samples were collected. All samples were stored at -80°C till laboratory analysis. IL-20 levels were measured by ELISA.
Results: IL-20 levels were significantly higher in patients with Periodontitis compared with healthy periodontal patients (p-value ≤ 0.05)
Conclusions: IL -20 play a role in Periodontitis patients.
Key words: IL-20, Periodontitis Patient, GCF