Year: 2023 | Month: December | Volume: 13 | Issue: 12 | Pages: 27-38
DOI: https://doi.org/10.52403/ijhsr.20231204
Quantitative Analysis of Post-Stroke Fatigue by Salivary Alpha Amylase as a Biochemical Marker
Varsha Sinduriya1, Prof. (Dr.) Ajeet Kumar Saharan2, Dr. Alisha Gracias3, Dr. Manisha Saharan4, Dr. Manoj Mathur5
1PhD Scholar, Dept. of Physiotherapy, MVG University, Jaipur
2Principal, Dept. of Physiotherapy, MVG University, Jaipur
3Assistant Professor, Goa Medical College, Goa
4Professor, JRNRV University, Udaipur
5Asst. Professor, Dept. of Physiotherapy, MVG University, Jaipur
Corresponding Author: Varsha Sinduriya
ABSTRACT
Objective: This Study was done to Objectively Quantify Post-Stroke Fatigue by Assessing Salivary Alpha Amylase Level as a Biochemical Marker and its relation to a Prescribed Exercise.
Method: Participants were grouped as Study Group (n=20) selected purposively according to Inclusion and Exclusion Criteria. For Control Group (n=30) were purposively selected according to Inclusion Criteria after the Mean and Standard Deviation of age constituting the Study Group. The groups were assessed for various Parameters and Pre- Salivary Sample was collected to assess Salivary Alpha Amylase Level and this was kept constant as Baseline Level. Each participant received Upper Limb and Lower Limb Exercise in successive day and Post-Salivary Samples were collected.
Results: Baseline Salivary Alpha Amylase release is higher among Stroke Survivors (26.75±32.81) than that of Control Group (10.51±6.30) with a mean difference of 16.24 which is Statistically Significant at (p<0.02). Stroke Survivors after Physiotherapy of Upper Limb release higher Salivary Alpha Amylase (40.51±38.95) than that of Control Group (15.83±11.05) with a mean difference of 24.68 which is Statistically Significant at (p<0.002). Stroke Survivors after Physiotherapy of Lower Limb release higher Salivary Alpha Amylase (38.63±43.68) than that of Control Group (22.05±18.86) with a mean difference of 16.58 which is Statistically Significant at (p<0.07).
Conclusions: These Findings indicate that Salivary Alpha-Amylase Activity in Subjects may be considered as a Significant Index of Stress in Individuals. Moreover, Salivary Alpha Amylase may be considered as a Biochemical Marker in Stroke Survivors for Assessment of Post Stroke Fatigue.
Key words: Stroke, Post Stroke Fatigue, Salivary Alpha Amylase