Year: 2023 | Month: November | Volume: 13 | Issue: 11 | Pages: 184-188
DOI: https://doi.org/10.52403/ijhsr.20231123
Myeloid Sarcoma in Lymph Node: An Uncommon Presentation in Case of Chronic Myeloid Leukemia
Monika Gupta1, Harsh Kumari2, Anjali Sindhu3, Sunita Singh4
1,2,3,4Department of Pathology, Pt. BDS, PGIMS, University of Health Sciences, Rohtak, India
Corresponding Author: Monika Gupta
ABSTRACT
Hematological malignancies may manifest as extramedullary soft tissue masses causing significant diagnostic and therapeutic dilemma. We herein report a case of 25-year-old male who presented with pain abdomen and lymphadenopathy, with no previous history of any haematological abnormality. A lymph node excision biopsy was conducted with simultaneous haematological work up. The case was finally diagnosed as extramedullary myeloid sarcoma in lymph node in newly detected case of CML in chronic phase.
Myeloid sarcomas (MS), may occur in isolation, or more commonly in patients with a history of myeloid malignancy. MS is an uncommon condition and exact mechanism of occurrence is unclear. It should be considered in the differential diagnosis of any atypical cellular infiltrate at any site. In all cases a thorough, diagnostic work-up including genetic profiling is important to stratify risk and guide treatment strategies.
Key words: Chronic Myeloid Leukemia, Lymph node, Myeloid Sarcoma