Year: 2023 | Month: October | Volume: 13 | Issue: 10 | Pages: 89-92
DOI: https://doi.org/10.52403/ijhsr.20231012
Renal Vascular Amyloidosis - A Brainstormer Manifestation of Autoimmune Diseases Spectrum
Khan Fatima1, Singhai Atin1, Gupta Vaibhav1, Babu Suresh1, Dhakad Urmila2
1Department of Pathology, King George’s Medical University, Lucknow, UP, India
2Department of Rheumatology, King George’s Medical University, Lucknow, UP, India
Corresponding Author: Atin Singhai
ABSTRACT
Chronic autoimmune diseases serve as a severe threat in long-term leading to renal manifestations. Renal vascular amyloidosis in itself is fatal with amyloid deposition occurs predominantly in renal arteries and arterioles. Renal vascular amyloidosis being an uncommon condition presents as diagnostic and therapeutic challenge for pathologists as well as clinicians. It presents with renal insufficiency without significant proteinuria, whereas glomerular amyloidosis presents with nephrotic range proteinuria. We present a case of renal vascular amyloidosis as a rare complication of long-term Psoriatic arthritis and Inflammatory bowel disease as well as presentation of amyloid deposition around arterioles of glomeruli instead of conventional nodular arrangement. This case highlights the importance of regular follow up and screening of patients with chronic autoimmune diseases on treatment to decrease renal morbidities and thereby reducing renal transplantation.
Key words: Amyloidosis, Autoimmune, Vessels