Review Article
Year: 2022 | Month: July | Volume: 12 | Issue: 7 | Pages: 250-270
DOI: https://doi.org/10.52403/ijhsr.20220737
mRNA Vaccine - Game Changer against Infectious Disease
Rashmi Subramanian1, Prabhu Meganathan1, Raja Selvarajan2
1Research Scientists, Hybrinomics Life Science & Diagnostics, Bangalore, Karnataka, India
1 Consultant Pathologist, Hybrinomics Life Science & Diagnostics, Bangalore, Karnataka, India.
2 Consultant Physician and Diabetologist, Kaveri Healthcare, Bangalore, Karnataka, India
Corresponding Author: Rashmi Subramanian
ABSTRACT
Millions of diseases are prevented each year by vaccines, saving thousands of lives. A variety of paediatric diseases have been significantly reduced over the past decade as a result of widespread vaccinations, including smallpox, measles, and polio. The ability of mRNA vaccines to evolve rapidly, their high potency, and the potential for low-cost and safe delivery, make them a promising alternative to traditional vaccines. However, until recently, their use was limited because to the instability and inefficiency of mRNA distribution in vivo. Non-infectious disorders, such as cancer, may not be amenable to traditional vaccine techniques. Due to this, there is a great need for more powerful and diverse vaccination platforms. This Review examines potential directions and problems in bringing this promising vaccination platform to mainstream therapeutic usage.
Key words: mRNA Vaccine, Infectious Disease, COVID-19 mRNA vaccines, vaccination drive .