Review of literature was prepared relevant to the study. The conceptual framework of the study was based on “Kenny’s open system model. Pilot study was done among patients in general medicine OPD in a selected hospital, Raipur. The main study was conducted in Orthopedics and Obstetrics & Gynecology OPDs  in a selected hospital, Raipur. A total of 90 patients included in the study and they were selected using convenient sampling. The instrument used for data collection was structured knowledge questionnaire. Validity and reliability of the tool was done. Data was collected for the period of 4 weeks. Descriptive and inferential statistics were used to analyse the data.
It was observed in present study that majority (70%) of the total sample in experimental and control group had inadequate level of knowledge regarding  prevention of Osteoporosis. And it was observed that the mean post test score of experimental group with standard deviation was 19.98±3.02 which was apparently higher than that of post test score of control group 14.11±4.74. Statistical differences were computed and the independent t value is 7.003 which was found significant at 0.05. Hence, Structured Teaching Programme was effective on knowledge regarding prevention of Osteoporosis. The study findings also shows that the association between knowledge score and educational status (ᵡ²=9.511, P=0.05), religion (ᵡ²=7.053, P=0.05) and previous knowledge (ᵡ²=46.44, P=0.05) were highly significant. Hence there was a significant association between pre-test knowledge and selected demographic variables of premenopausal women such as age, gender, education, income, religion, marital status, dietary pattern, age of menarche, age of marriage and previous knowledge.